An Open-Label Multidose Psilocybin Intervention for Obsessive-Compulsive Disorder

Preprint, not peer reviewed. Tiwari P, Nayak SM, Sepeda ND et al.. medRxiv, 5 Oct 2026.

Tags: Human, Preprint, Psilocybin, Depression, Anxiety, OCD.

Weekly Science Digest, 3 Oct 2026 to 9 Oct 2026, finding 7: On the preprint servers

waitlist-controlled open-label multidose psilocybin in 30 treatment-resistant OCD patients at Johns Hopkins; feasibility and safety first, efficacy unblinded

How much weight it carries: Not peer reviewed. Early results that may not hold up. (Preprint)

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