Mechanisms of vesicular monoamine transporter 2 modulation by amphetamines and lobeline

Paper. Wu D, Liu C, Wang H et al.. Cell Reports, 26 Oct 2026.

Tags: MDMA, Addiction.

Weekly Science Digest, 23 Oct 2026 to 29 Oct 2026, finding 5: In brief

Cryo-EM structures of human VMAT2 bound to MDMA, MDA, amphetamine and methamphetamine show they act as substrates, not blockers