Real-world use, safety, and mental health efficacy of regulated psilocybin services in Oregon and Colorado

Preprint, not peer reviewed. Thompson SM, Effinger DP, Novick AM et al.. medRxiv, 12 Aug 2026.

Tags: Human, Preprint, Psilocybin, Anxiety.

Weekly Science Digest, 3 Oct 2026 to 9 Oct 2026, finding 7: On the preprint servers

retrospective data on 2,363 clients of Oregon and Colorado service centers reports PHQ-9 down 49% at two weeks, with no difference above and below 30 mg

How much weight it carries: Not peer reviewed. Early results that may not hold up. (Preprint)

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